Bacterial secretion systems

secretion systems

 

Type 1 SS:

  1. In gram positive and negative bacteria
  2. Unknown in archaea
  3. Transport proteins and peptides
  4. Also known as ABC transporters
  5. Comprise an ATP binding cassette
  6. Outer membrane binding factor
  7. And membrane fusion proteins

 

Type 2 SS:

  1. In gram negative bacteria
  2. Not in gram positive
  3. Also in Achaea
  4. Uses sec or tat transport system to transport into periplasmic space
  5. Transports proteins, enzymes, toxins
  6. Proteins can cross the outer membrane unassisted

 

Type 3 SS:

  1. In gram negative bacteria
  2. Not in achaea or gram positives
  3. Transport effector proteins
  4. Have needle like structures that inject protein into host cell

 

Type 4 SS:

  1. In gram negative and achaea and gram pos
  2. Have unique ability to transport both DNA and proteins
  3. In gram positive used to transport dna in conjugation
  4. In gram negative used to transport both proteins and dna in conjugation

 

Type 5 SS:

  1. In gram negative
  2. Not in gram positive
  3. Unknown in achaea
  4. Uses sec or tat and then autotransporters
  5. Transport over 500 different types of protein
  6. Have roles in virulence

 

Type 6 SS:

  1. In gram negative
  2. Not in gram positive or achaea
  3. Use injection system similar to that of phage
  4. Spike like injectosome
  5. Key roles in virulence
  6. Transport effector proteins

 

Type 7 SS:

  1. In gram positive bacteria
  2. Not in gram negative or achaea
  3. Key roles in virulence
  4. Transport virulence factors
  5. First found in mycobacteria
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